RM6786

Phospho-ACC(S79) (18C10) Rabbit Monoclonal Antibody

ACAC; ACACA; ACACB; ACC alpha; ACC; ACC beta; ACC1; ACC2; ACCA; ACCB; Acetyl CoA carboxylase 1; Acetyl CoA carboxylase 2;COA1; COA2;

Affinity-chromatography

常规抗体

ACACA

ACAC, ACC1, ACCA

WB

Human,Mouse,Rat

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

31

Q13085

WB 1:500~1:2000

266kDa

Rabbit IgG

Phospho-ACC(S79) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Expressed in brain, placenta, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver

Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q5SWU9}

Cytosolic enzyme that catalyzes the carboxylation of acetyl- CoA to malonyl-CoA, the first and rate-limiting step of de novo fatty acid biosynthesis (PubMed:20952656, PubMed:20457939, PubMed:29899443). This is a 2 steps reaction starting with the ATP-dependent carboxylation of the biotin carried by the biotin carboxyl carrier (BCC) domain followed by the transfer of the carboxyl group from carboxylated biotin to acetyl-CoA (PubMed:20952656, PubMed:20457939, PubMed:29899443).

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