产品名称
SNAP29 (10N2) Rabbit Monoclonal Antibody
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
O95721
免疫原
A synthetic peptide of human SNAP29
稀释度
WB: 1:1000-1:5000 ICC/IF: 1:20-1:100 FC: 1:20 IP: 1:20
注意事项
SNAP29 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Found in brain, heart, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas
细胞定位
Cytoplasm. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9Z2P6}; Peripheral membrane protein. Cytoplasmic vesicle, autophagosome membrane; Peripheral membrane protein. Cell projection, cilium membrane; Peripheral membrane protein. Note=Appears to be mostly membrane-bound, probably via interaction with syntaxins, but a significant portion is cytoplasmic Localizes to the ciliary pocket from where the cilium protrudes
功能
SNAREs, soluble N-ethylmaleimide-sensitive factor-attachment protein receptors, are essential proteins for fusion of cellular membranes. SNAREs localized on opposing membranes assemble to form a trans-SNARE complex, an extended, parallel four alpha-helical bundle that drives membrane fusion. SNAP29 is a SNARE involved in autophagy through the direct control of autophagosome membrane fusion with the lysososome membrane. Plays also a role in ciliogenesis by regulating membrane fusions.
