RM6742

TTF1 (17D1) Rabbit Monoclonal Antibody

BCH; BHC; NK2; NKX2.1; NKX2A; TEBP; Thyroid nuclear factor 1; Tinman; TITF1; TTF1;

Affinity-chromatography

常规抗体

NKX2-1

NKX2A, TITF1, TTF1

WB

Human,Mouse,Rat

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

7080

P43699

WB 1:500~1:2000 IHC 1:50~1:200

39kDa

Rabbit IgG

TTF1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Thyroid and lung.

Nucleus {ECO:0000250|UniProtKB:P50220}.

Transcription factor that binds and activates the promoter of thyroid specific genes such as thyroglobulin, thyroperoxidase, and thyrotropin receptor. Crucial in the maintenance of the thyroid differentiation phenotype. May play a role in lung development and surfactant homeostasis. Forms a regulatory loop with GRHL2 that coordinates lung epithelial cell morphogenesis and differentiation. Activates the transcription of GNRHR and plays a role in enhancing the circadian oscillation of its gene expression. Represses the transcription of the circadian transcriptional repressor NR1D1 (By similarity).

现货