产品名称
ORP1 (13L15) Rabbit Monoclonal Antibody
别名
ORP1; OSBP8; OSBPL1; OSBPL1A; OSBPL1B;
纯度
Affinity-chromatography
蛋白名称
ORP1, OSBP8, OSBPL1, OSBPL1B
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q9BXW6
免疫原
A synthetic peptide of human ORP1
稀释度
WB: 1:1000 ICC/IF: 1:20 FC: 1:20 IP: 1:20
注意事项
ORP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Late endosome. Note=Colocalizes with RAB7A, RAB9A and LAMP1 in late endosomes
功能
Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A (PubMed:
16176980). Binds 25-hydroxycholesterol and cholesterol (PubMed:
17428193).
