产品名称
TYSD1 Rabbit Polyclonal Antibody
蛋白名称
Peroxisomal leader peptide-processing protease (EC 3.4.21.-) (Trypsin domain-containing protein 1) [Cleaved into: Peroxisomal leader peptide-processing protease, 15 kDa form; Peroxisomal leader peptide-processing protease, 45 kDa form]
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q2T9J0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q2T9J0/entry
Mouse Swissprot No.
Q9DBA6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9DBA6
免疫原
Synthesized peptide derived from human protein . at AA range: 120-200
特异性
TYSD1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protease that removes the N-terminal peroxisomal targeting signal (PTS2) from proteins produced in the cytosol, thereby facilitating their import into the peroxisome. The encoded protein is also capable of removing the C-terminal peroxisomal targeting signal (PTS1) from proteins in the peroxisomal matrix. The full-length protein undergoes self-cleavage to produce shorter, potentially inactive, peptides. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013],
功能
function:Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and the specific processing of PTS1 proteins. May participate to a regulatory mechanism that control the peroxisomal beta-oxidation of fatty acids.,PTM:Processed into the 49 kDa and the 10 kDa forms upon import into the peroxisomes. The 49 kDa form probably corresponds to the mature enzyme, while the 10 kDa form may represent an inhibitory N-terminal fragment which prevents protease activity until it reaches the peroxisomes.,similarity:Belongs to the peptidase S1B family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
