RM6695

HLA DMB (14D11) Rabbit Monoclonal Antibody

DMB; RING7;

Affinity-chromatography

常规抗体

HLA-DMB

DMB, RING7

WB

Human

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

3109

P28068

WB 1:500~1:2000 FC 1:50

29kDa

Rabbit IgG

HLA DMB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Late endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Note=Localizes to late endocytic compartment. Associates with lysosome membranes

Plays a critical role in catalyzing the release of class II- associated invariant chain peptide (CLIP) from newly synthesized MHC class II molecules and freeing the peptide binding site for acquisition of antigenic peptides. In B-cells, the interaction between HLA-DM and MHC class II molecules is regulated by HLA-DO.

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