产品名称
GLU2B (11D10) Rabbit Monoclonal Antibody
别名
G19P1; PCLD; PKCSH; PLD1; PRKCSH;
纯度
Affinity-chromatography
基因名称
PRKCSH {ECO:0000303|PubMed:28375157, ECO:0000312|HGNC:HGNC:9411}
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P14314
稀释度
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
注意事项
GLU2B Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Endoplasmic reticulum {ECO:0000255|PROSITE- ProRule:PRU10138, ECO:0000305|PubMed:10929008}
功能
Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc(2)Man(9)GlcNAc(2) oligosaccharide precursor of immature glycoproteins (PubMed:
10929008). Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia (By similarity).
