RM6688

CD79b (1O8) Rabbit Monoclonal Antibody

B29; CD79b; IGB; Igbeta;

Affinity-chromatography

常规抗体

CD79B

B29, IGB

WB

Human

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

974

P40259

WB 1:500~1:2000 ICC/IF 1:50~1:200 FC 1:50

26kDa

Rabbit IgG

CD79b Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

B-cells.

Cell membrane; Single-pass type I membrane protein. Note=Following antigen binding, the BCR has been shown to translocate from detergent-soluble regions of the cell membrane to lipid rafts although signal transduction through the complex can also occur outside lipid rafts.

Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.

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