RM6685

CD24 (11S3) Rabbit Monoclonal Antibody

CD24; CD24 antigen; CD24A; HAS; Signal transducer CD24;

Affinity-chromatography

常规抗体

CD24

CD24A

WB

Human

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

100133941

P25063

WB 1:500~1:2000 IP 1:50

8kDa

Rabbit IgG

CD24 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

B-cells. Expressed in a number of B-cell lines including P32/ISH and Namalwa. Expressed in erythroleukemia cell and small cell lung carcinoma cell lines. Also expressed on the surface of T-cells.

Cell membrane; Lipid-anchor, GPI-anchor.

May have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin- like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells (PubMed:11313396). In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity (By similarity).

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