产品名称
CHD3 (5M11) Rabbit Monoclonal Antibody
别名
Chd3; Chd7; hZFH; Mi2 ALPHA; Prp7; Prp9 1; ZFH;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q12873
注意事项
CHD3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Nucleus, PML body. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Associates with centrosomes in interphase and mitosis.
功能
Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones (PubMed:
9804427, PubMed:
30397230). Involved in transcriptional repressiobn as part of the NuRD complex (PubMed:
27068747). Required for anchoring centrosomal pericentrin in both interphase and mitosis, for spindle organization and centrosome integrity (PubMed:
17626165).
