产品名称
GBP1 (19P9) Rabbit Monoclonal Antibody
别名
GBP1; GTP binding protein 1; Guanine nucleotide binding protein 1; Guanylate binding protein 1; HuGBP1; Interferon induced guanylate binding protein 1;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P32455
免疫原
A synthetic peptide of human GBP1
稀释度
WB: 1:1000 IHC: 1:20 ICC/IF: 1:50
注意事项
GBP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cytoplasm. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Cell membrane Secreted. Note=Secreted from endothelial cells in the cerebrospinal fluid, upon bacterial challenge and independently of IFNG induction Golgi membrane localization requires isoprenylation and the presence of another IFNG-induced factor
功能
Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes.
