RM6633

UBE4B (1H16) Rabbit Monoclonal Antibody

HDNB1; Ube4b; UBOX3; UFD2; UFD2a; Ufd2p;

Affinity-chromatography

常规抗体

UBE4B

WB

Human,Mouse,Rat

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

10277

O95155

WB 1:500~1:2000

146kDa

Rabbit IgG

UBE4B Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Expressed in differentiated myotubes (at protein level) (PubMed:17369820). Highest expression in ovary, testis, heart and skeletal muscle (PubMed:11802788). Expression is low in colon, thymus and peripheral blood leukocytes (PubMed:11802788). Almost undetectable in lung and spleen (PubMed:11802788)

Cytoplasm. Nucleus {ECO:0000250|UniProtKB:Q9ES00}

Ubiquitin-protein ligase that probably functions as an E3 ligase in conjunction with specific E1 and E2 ligases (By similarity). May also function as an E4 ligase mediating the assembly of polyubiquitin chains on substrates ubiquitinated by another E3 ubiquitin ligase (By similarity). May regulate myosin assembly in striated muscles together with STUB1 and VCP/p97 by targeting myosin chaperone UNC45B for proteasomal degradation (PubMed:17369820).

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