产品名称
Themis (18F8) Rabbit Monoclonal Antibody
别名
Protein THEMIS; SPOT; THEMIS; TSEPA;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q8N1K5
稀释度
WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
注意事项
Themis Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Cytoplasm {ECO:0000250|UniProtKB:Q8BGW0}. Nucleus {ECO:0000250|UniProtKB:Q8BGW0}
功能
Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk.
