RM6622

FACL4 (17M4) Rabbit Monoclonal Antibody

ACS4; Acsl4; acyl CoA synthetase 4; FACL4; Fatty acid Coenzyme A ligase; LACS4; Long chain 4; long chain fatty acid Coenzyme A ligase 4; MRX63; MRX68;

Affinity-chromatography

常规抗体

ACSL4

ACS4, FACL4, LACS4

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

2182

O60488

Recombinant protein of human FACL4

WB: 1:1000 IHC: 1:100-1:200 ICC/IF: 1:50

79kDa

79kDa

Rabbit IgG

FACL4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein. Cell membrane

Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation (PubMed:24269233, PubMed:22633490, PubMed:21242590). Preferentially activates arachidonate and eicosapentaenoate as substrates (PubMed:21242590). Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET. Modulates glucose- stimulated insulin secretion by regulating the levels of unesterified EETs (By similarity). Modulates prostaglandin E2 secretion (PubMed:21242590).

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