产品名称
P2RX4 Rabbit Polyclonal Antibody
蛋白名称
P2X purinoceptor 4 (P2X4) (ATP receptor) (Purinergic receptor)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q99571
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q99571/entry
Mouse Swissprot No.
Q9JJX6
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9JJX6
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941P51577
免疫原
Synthesized peptide derived from human protein . at AA range: 150-230
特异性
P2RX4 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene. [provided by RefSeq, Feb 2012],
组织表达
Blood,Brain,Kidney,Liver,
细胞定位
Membrane ; Multi-pass membrane protein .
信号通路
Calcium;Neuroactive ligand-receptor interaction;
功能
function:Receptor for ATP that acts as a ligand gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin.,online information:P2X receptor entry,similarity:Belongs to the P2X receptor family.,subunit:Homo- or heteropolymers.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
