产品名称
RCHY1 (11B14) Rabbit Monoclonal Antibody
别名
ARNIP; CHIMP; hARNIP; hPirh2; PIRH2E; PIRH2F; RCHY1; RNF199; ZCHY; ZNF363;
纯度
Affinity-chromatography
蛋白名称
ARNIP, CHIMP, PIRH2, RNF199, ZNF363
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q96PM5
稀释度
WB 1:500~1:2000 ICC/IF 1:50~1:200 IP 1:50
注意事项
RCHY1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Nucleus. Nucleus speckle. Cytoplasm.
功能
Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.
