产品名称
RCHY1 (11B14) Rabbit Monoclonal Antibody
别名
ARNIP; CHIMP; hARNIP; hPirh2; PIRH2E; PIRH2F; RCHY1; RNF199; ZCHY; ZNF363;
纯度
Affinity-chromatography
蛋白名称
ARNIP, CHIMP, PIRH2, RNF199, ZNF363
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q96PM5
注意事项
RCHY1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Nucleus. Nucleus speckle. Cytoplasm.
功能
Mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including p53/TP53, P73, HDAC1 and CDKN1B. Preferentially acts on tetrameric p53/TP53. Monoubiquitinates the translesion DNA polymerase POLH. Contributes to the regulation of the cell cycle progression. Increases AR transcription factor activity.
