产品名称
PDE2A (16J7) Rabbit Monoclonal Antibody
别名
CGS PDE; cGSPDE; PDE2A; PDE2A1; PDE2A4; phosphodiesterase 2A;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
O00408
注意事项
PDE2A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in brain and to a lesser extent in heart, placenta, lung, skeletal muscle, kidney and pancreas
细胞定位
[Isoform PDE2A3]: Cell membrane; Lipid- anchor [Isoform PDE2A1]: Cytoplasm
功能
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Plays an important role in growth and invasion of malignant melanoma cells (e.g. pseudomyxoma peritonei (PMP) cell line) (PubMed:
24705027).
