产品名称
CNTP2 (18E14) Rabbit Monoclonal Antibody
别名
AUTS15; CDFE; CNTNAP2; CNTP2; NRXN4; PTHSL1;
纯度
Affinity-chromatography
蛋白名称
CASPR2 {ECO:0000303|PubMed:10624965}, KI
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q9UHC6
稀释度
WB 1:500~1:1000 IHC 1:100~1:500
注意事项
CNTP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Predominantly expressed in nervous system.
细胞定位
Membrane {ECO:0000250|UniProtKB:Q9CPW0}; Single- pass type I membrane protein. Cell projection, axon {ECO:0000250|UniProtKB:Q9CPW0}. Cell junction, paranodal septate junction {ECO:0000250|UniProtKB:Q9CPW0}. Note=Expressed in the juxtaparadonal region. {ECO:0000250|UniProtKB:Q9CPW0}
功能
Required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction.
