产品名称
Monoacylglycerol Lipase (19P2) Rabbit Monoclonal Antibody
别名
HUK5; Lysophospholipase homolog; Lysophospholipase like; MAGL; MGL; MGLL;Monoacylglycerol lipase;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q99685
注意事项
Monoacylglycerol Lipase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Detected in adipose tissue, lung, liver, kidney, brain and heart.
细胞定位
Cytoplasm, cytosol {ECO:0000250|UniProtKB:O35678}. Membrane {ECO:0000250|UniProtKB:O35678}; Peripheral membrane protein {ECO:0000250|UniProtKB:O35678}
功能
Converts monoacylglycerides to free fatty acids and glycerol (PubMed:
19029917, PubMed:
20079333, PubMed:
21049984, PubMed:
22969151, PubMed:
24368842). Hydrolyzes the endocannabinoid 2- arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (PubMed:
19029917, PubMed:
20079333, PubMed:
21049984, PubMed:
22969151, PubMed:
24368842). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth (PubMed:
20079333).
