产品名称
CNTP2 (18E14) Rabbit Monoclonal Antibody
别名
AUTS15; CDFE; CNTNAP2; CNTP2; NRXN4; PTHSL1;
纯度
Affinity-chromatography
蛋白名称
CASPR2 {ECO:0000303|PubMed:10624965}, KI
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q9UHC6
注意事项
CNTP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Predominantly expressed in nervous system.
细胞定位
Membrane {ECO:0000250|UniProtKB:Q9CPW0}; Single- pass type I membrane protein. Cell projection, axon {ECO:0000250|UniProtKB:Q9CPW0}. Cell junction, paranodal septate junction {ECO:0000250|UniProtKB:Q9CPW0}. Note=Expressed in the juxtaparadonal region. {ECO:0000250|UniProtKB:Q9CPW0}
功能
Required for gap junction formation (Probable). Required, with CNTNAP1, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the juxtaparanodal region of the axo-glial junction.
