产品名称
NUDC3 Rabbit Polyclonal Antibody
蛋白名称
NudC domain-containing protein 3
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q8IVD9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8IVD9/entry
Mouse Swissprot No.
Q8R1N4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8R1N4
免疫原
Synthesized peptide derived from human protein . at AA range: 30-110
特异性
NUDC3 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
The product of this gene functions to maintain the stability of dynein intermediate chain. Depletion of this gene product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle microtubules, and spindle poles, and loss of gamma-tubulin from spindle poles. The protein localizes to the Golgi apparatus during interphase, and levels of the protein increase after the G1/S transition. [provided by RefSeq, Jul 2008],
组织表达
Brain,Epithelium,Pancreas,Placenta,
功能
PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 CS domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.