产品名称
APLP2 (17Z11) Rabbit Monoclonal Antibody
别名
Aplp2; APPH; APPL2; CDEBP;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q06481
免疫原
A synthetic peptide of human APLP2
稀释度
WB: 1:2000-1:10000 IHC: 1:50
注意事项
APLP2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues
细胞定位
Cell membrane; Single-pass type I membrane protein. Nucleus
功能
May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity).