产品名称
GOT2 (13J19) Rabbit Monoclonal Antibody
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P00505
免疫原
A synthetic peptide of human FABP-1
稀释度
WB: 1:1000 IHC: 1:20 FC: 1:20-1:100 IP: 1:20
注意事项
GOT2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Mitochondrion matrix. Cell membrane. Note=Exposure to alcohol promotes translocation to the cell membrane.
功能
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). As a member of the malate-aspartate shuttle, it has a key role in the intracellular NAD(H) redox balance. Is important for metabolite exchange between mitochondria and cytosol, and for amino acid metabolism. Facilitates cellular uptake of long-chain free fatty acids.