产品名称
EDG3 (14L5) Rabbit Monoclonal Antibody
别名
EDG3; LPB3; S1P receptor 3; S1P3; S1pr3;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q99500
稀释度
WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
注意事项
EDG3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed in all tissues, but most abundantly in heart, placenta, kidney, and liver
细胞定位
Cell membrane; Multi-pass membrane protein.
功能
Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.
