产品名称
PDLIM1 (1G17) Rabbit Monoclonal Antibody
别名
CLIM1; CLP36; Elfin; Enigma; hCLIM1; Pdlim1;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
O00151
免疫原
A synthetic peptide of human PDLIM1
稀释度
WB: 1:1000 ICC/IF: 1:50 FC: 1:20-1:100 IP: 1:20
注意事项
PDLIM1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung. A lower level expression is seen in liver, thymus, kidney, prostate and pancreas and is not found in the brain, testis, ovary, and peripheral blood leukocytes
细胞定位
Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line Note=Associates with actin stress fibers
功能
Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton (PubMed:
10861853). Involved in assembly, disassembly and directioning of stress fibers in fibroblasts. Required for the localization of ACTN1 and PALLD to stress fibers. Required for cell migration and in maintaining cell polarity of fibroblasts (By similarity).