产品名称
IRF4 (6T2) Rabbit Monoclonal Antibody
别名
Interferon regulatory factor 4; Irf4; LSIRF; MUM1; NFEM5;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q15306
免疫原
A synthetic peptide of human MUM1
稀释度
WB: 1:1000 IHC: 1:50 IP: 1:20
注意事项
IRF4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
功能
Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8(+) dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA- 3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes (By similarity).
