产品名称
DBF4 (15O15) Rabbit Monoclonal Antibody
别名
ASK; CHIF; DBF4; DBF4 zinc finger A; DBF4A; ZDBF1;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q9UBU7
免疫原
A synthetic peptide of human DBF4
注意事项
DBF4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Highly expressed in testis and thymus. Expressed also in most cancer cells lines.
功能
Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7- DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.
