产品名称
M6PR (4S19) Rabbit Monoclonal Antibody
别名
CD MPR; M6pr; Man6PR; MPR46; MPRD; SMPR;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P20645
稀释度
WB 1:500~1:2000 ICC/IF 1:50~1:200 FC 1:50
注意事项
M6PR Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Lysosome membrane; Single-pass type I membrane protein
功能
Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.
