RM6429

CLPP (1P6) Rabbit Monoclonal Antibody

Endopeptidase Clp;

Affinity-chromatography

常规抗体

CLPP

WB

Human,Mouse,Rat

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

8192

Q16740

A synthetic peptide of human CLPP

WB: 1:1000-1:5000 FC: 1:20 IP: 1:20

30kDa

30kDa

Rabbit IgG

CLPP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Detected in liver (at protein level). Predominantly expressed in skeletal muscle. Intermediate levels in heart, liver and pancreas. Low in brain, placenta, lung and kidney

Mitochondrion matrix

Protease component of the Clp complex that cleaves peptides and various proteins in an ATP-dependent process. Has low peptidase activity in the absence of CLPX. The Clp complex can degrade CSN1S1, CSN2 and CSN3, as well as synthetic peptides (in vitro) and may be responsible for a fairly general and central housekeeping function rather than for the degradation of specific substrates (PubMed:11923310, PubMed:15522782). Cleaves PINK1 in the mitochondrion (PubMed:22354088).

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