RM6413

GRIK2 (18A14) Rabbit Monoclonal Antibody

EAA4; GLR6; MRT6; GLUK6; GLUR6; GluK2;

Affinity-chromatography

常规抗体

GRIK2

GLUR6

WB

Human,Mouse,Rat

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

2898

Q13002

WB 1:500~1:2000 IHC 1:50~1:200

103kDa

Rabbit IgG

GRIK2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Expression is higher in cerebellum than in cerebral cortex

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein

Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist (PubMed:28180184). Modulates cell surface expression of NETO2 (By similarity).

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