RM6402

PSAP (10Q13) Rabbit Monoclonal Antibody

GLBA; SAP1; Saposins; Dispersin;

Affinity-chromatography

常规抗体

PSAP

GLBA, SAP1

WB

Human

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

5660

P07602

WB 1:1000~1:5000 IHC 1:50~1:200

58kDa

Rabbit IgG

PSAP Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Lysosome

Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.2.1.46). Saposin- C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate. Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3.1.4.12). Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases.

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