产品名称
STXBP1 (6W16) Rabbit Monoclonal Antibody
别名
P67; NSEC1; UNC18; RBSEC1; MUNC18-1;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P61764
免疫原
A synthetic peptide of human Munc18-1
稀释度
WB: 1:1000 ICC/IF: 1:100 IP: 1:20
注意事项
STXBP1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Brain and spinal cord. Highly enriched in axons.
细胞定位
Cytoplasm, cytosol. Membrane; Peripheral membrane protein
功能
Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins (By similarity). Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
