RM6355

RAD23A (17F4) Rabbit Monoclonal Antibody

hHR23A; HR23A; RAD 23a; RAD23A;

Affinity-chromatography

常规抗体

RAD23A

WB

Human,Mouse,Rat

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

5886

P54725

A synthetic peptide of human hHR23A

WB: 1:2000-1:10000 FC: 1:20

52kDa

40kDa

Rabbit IgG

RAD23A Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Nucleus.

Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'- linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. (Microbial infection) Involved in Vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 Vpr with the host proteasome.

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