产品名称
KLRG1 (2X10) Rabbit Monoclonal Antibody
别名
2F1 Ag; CLEC15A; KLRG1; MAFA 2F1; MAFA L; MAFA like; MAFAL;
纯度
Affinity-chromatography
蛋白名称
CLEC15A, MAFA, MAFAL
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q96E93
注意事项
KLRG1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells.
细胞定位
Cell membrane; Single-pass type II membrane protein
功能
Plays an inhibitory role on natural killer (NK) cells and T- cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E- cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.
