产品名称
KDM4B / JMJD2B (8R15) Rabbit Monoclonal Antibody
别名
JHDM3B; JMJD2B; Kdm4b; TDRD14B;
纯度
Affinity-chromatography
蛋白名称
JHDM3B, JMJD2B, KIAA0876
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
O94953
免疫原
A synthetic peptide of human KDM4B/JMJD2B
稀释度
WB: 1:1000 IHC: 1:20 ICC/IF: 1:200 FC: 1:200
注意事项
KDM4B / JMJD2B Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00537, ECO:0000269|PubMed:15927959}
功能
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys- 20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
