产品名称
SC65 Rabbit Polyclonal Antibody
蛋白名称
Synaptonemal complex protein SC65 (Leprecan-like protein 4) (Nucleolar autoantigen No55)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q92791
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q92791/entry
Mouse Swissprot No.
Q8K2B0
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8K2B0
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q64375
免疫原
Synthesized peptide derived from human protein . at AA range: 380-460
特异性
SC65 Polyclonal Antibody detects endogenous levels of protein.
宿主
Polyclonal, Rabbit,IgG
背景介绍
This nucleolar protein was first characterized because it was an autoantigen in cases on interstitial cystitis. The protein, with a predicted molecular weight of 50 kDa, appears to be localized in the particulate compartment of the interphase nucleolus, with a distribution distinct from that of nucleolar protein B23. During mitosis it is associated with chromosomes. [provided by RefSeq, Jul 2008],
组织表达
Detected in fibroblasts (at protein level) (PubMed:23959653). Detected in spleen, prostate, testis, ovary, colon, pancreas, kidney, placenta and heart (PubMed:10952778).
细胞定位
Endoplasmic reticulum .
功能
similarity:Belongs to the CRTAP/No55 family.,subcellular location:Localized uniformly throughout the granular component of the nucleolus and on the surface of chromosomes during mitosis.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.