产品名称
TXNRD2 (12B7) Rabbit Monoclonal Antibody
别名
SelZ; TR 3; TR; TR beta; TR3; TRXR2; TXNRD 2; Txnrd2;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q9NNW7
免疫原
A synthetic peptide of human TXNRD2
稀释度
WB: 1:1000-1:5000 IHC: 1:20
注意事项
TXNRD2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low. High expression is observed in the adrenal cortex (PubMed:24601690).
功能
Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis (PubMed:
24601690). Maintains thioredoxin in a reduced state. May play a role in redox- regulated cell signaling.
