产品名称
ATP1B1 (18D16) Rabbit Monoclonal Antibody
别名
Adenosinetriphosphatase; ATP1B; ATP1B1; Atpb 1; ATPBS;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
P05026
免疫原
A synthetic peptide of human beta 1 Sodium Potassium ATPase
稀释度
WB: 1:1000-1:5000 IHC: 1:20-1:50
注意事项
ATP1B1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Found in most tissues.
细胞定位
Cell membrane; Single-pass type II membrane protein. Apical cell membrane {ECO:0000250|UniProtKB:P07340}; Single-pass type II membrane protein. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:P14094}. Note=Colocalizes with OBSCN at the intercalated disk and sarcolemma in cardiomyocytes. Localizes in long striations at the level of Z and M lines {ECO:0000250|UniProtKB:P14094}
功能
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane.
