产品名称
NUFP1 Rabbit Polyclonal Antibody
蛋白名称
Nuclear fragile X mental retardation-interacting protein 1 (Nuclear FMRP-interacting protein 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q9UHK0
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UHK0/entry
Mouse Swissprot No.
Q9QXX8
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q9QXX8
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q641W3
免疫原
Synthesized peptide derived from human protein . at AA range: 180-260
特异性
NUFP1 Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a nuclear RNA binding protein that contains a C2H2 zinc finger motif and a nuclear localization signal. This protein is associated with the nuclear matrix in perichromatin fibrils and, in neurons, localizes to the cytoplasm in association with endoplasmic reticulum ribosomes. This protein interacts with the fragile X mental retardation protein (FMRP), the tumor suppressor protein BRCA1, upregulates RNA polymerase II transcription, and is involved in box C/D snoRNP biogenesis. A pseudogene of this gene resides on chromosome 6q12. [provided by RefSeq, Feb 2012],
组织表达
Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas.
细胞定位
Nucleus . Distributed in the nucleus in a dot-like pattern.
功能
function:Binds RNA.,similarity:Contains 1 C2H2-type zinc finger.,subcellular location:Distributed in the nucleus in a dot-like pattern.,subunit:Interacts with FMR1.,tissue specificity:Expressed in spleen, thymus, prostate, testis, ovary, small intestine, colon, peripheral blood leukocyte, heart, brain, placenta, lung, liver, skeletal muscle, kidney, and pancreas.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
