产品名称
MYL9 (19Z8) Rabbit Monoclonal Antibody
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P24844
稀释度
WB 1:500~1:2000 IHC 1:50~1:200 IP 1:50
注意事项
MYL9 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Smooth muscle tissues and in some, but not all, nonmuscle cells.
细胞定位
Cytoplasm, cytoskeleton {ECO:0000250|UniProtKB:Q9CQ19}. Cytoplasm, cell cortex {ECO:0000250|UniProtKB:Q9CQ19}. Note=Colocalizes with F-actin, MYH9 and PIEZO1 at the actomyosin cortex in myoblasts {ECO:0000250|UniProtKB:Q9CQ19}
功能
Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (PubMed:
11942626, PubMed:
2526655). In myoblasts, may regulate PIEZO1-dependent cortical actomyosin assembly involved in myotube formation (By similarity).