产品名称
CD97 (14Q9) Rabbit Monoclonal Antibody
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P48960
稀释度
WB 1:500~1:2000 IHC 1:50~1:200 FC 1:50
注意事项
CD97 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Broadly expressed, found on most hematopoietic cells, including activated lymphocytes, monocytes, macrophages, dendritic cells, and granulocytes. Expressed also abundantly by smooth muscle cells. Expressed in thyroid, colorectal, gastric, esophageal and pancreatic carcinomas too. Expression are increased under inflammatory conditions in the CNS of multiple sclerosis and in synovial tissue of patients with rheumatoid arthritis. Increased expression of CD97 in the synovium is accompanied by detectable levels of soluble CD97 in the synovial fluid
细胞定位
Cell membrane {ECO:0000250|UniProtKB:Q9Z0M6}; Multi-pass membrane protein
功能
Receptor potentially involved in both adhesion and signaling processes early after leukocyte activation. Plays an essential role in leukocyte migration.
