产品名称
Apolipoprotein CI (10F18) Rabbit Monoclonal Antibody
别名
APO C1; Apo CI; APOC 1; ApoC I; APOC1; APOC1B; ApolipoproteinCI;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
P02654
稀释度
WB 1:500~1:1000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50
注意事项
Apolipoprotein CI Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Synthesized mainly in liver and to a minor degree in intestine. Also found in the lung and spleen
功能
Inhibitor of lipoprotein binding to the low density lipoprotein (LDL) receptor, LDL receptor-related protein, and very low density lipoprotein (VLDL) receptor. Associates with high density lipoproteins (HDL) and the triacylglycerol-rich lipoproteins in the plasma and makes up about 10% of the protein of the VLDL and 2% of that of HDL. Appears to interfere directly with fatty acid uptake and is also the major plasma inhibitor of cholesteryl ester transfer protein (CETP). Binds free fatty acids and reduces their intracellular esterification. Modulates the interaction of APOE with beta-migrating VLDL and inhibits binding of beta-VLDL to the LDL receptor-related protein.
