产品名称
Epac2 (19F17) Rabbit Monoclonal Antibody
别名
CAMP GEFII; CAMPGEFII; CGEF2; EPAC2; Rapgef4;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q8WZA2
注意事项
Epac2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Predominantly expressed in brain and adrenal gland. Isoform 2 is expressed in liver. Isoform 1 is expressed in liver at very low levels
细胞定位
Cytoplasm. Membrane; Peripheral membrane protein
功能
Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2 (By similarity).
