产品名称
Tin2 (16N6) Rabbit Monoclonal Antibody
别名
DKCA3; Tin 2; TIN2; TINF 2; Tinf2;
纯度
Affinity-chromatography
存储缓冲液
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Human Swissprot No.
Q9BSI4
注意事项
Tin2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas
细胞定位
Nucleus. Chromosome, telomere. Note=Associated with telomeres
功能
Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.
