RM6178

45567(3A2) Rabbit Monoclonal Antibody

Oct 2; Octamer binding transcription factor 2; OTF2; POU domain; POU2F2;

Affinity-chromatography

常规抗体

POU2F2

OCT2, OTF2

WB

Human

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.

5452

P09086

A synthetic peptide of human Oct-2

WB: 1:1000 IHC: 1:50 ICC/IF: 1:50 FC: 1:20

55kDa

51kDa

Rabbit IgG

Oct-2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Isoform 3 is B-cell specific. Isoform 5 is expressed in B-cells and the immunoglobulin-expressing T-cell line MOLT-4, but not in the T-cell line BW5147.

Cytoplasm. Nucleus.

Transcription factor that specifically binds to the octamer motif (5'-ATTTGCAT-3') (PubMed:2904654, PubMed:7859290). Regulates IL6 expression in B cells with POU2AF1 (By similarity). Regulates transcription in a number of tissues in addition to activating immunoglobulin gene expression (PubMed:2901913, PubMed:2904654). Modulates transcription transactivation by NR3C1, AR and PGR (PubMed:10480874).

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