产品名称
EWSR1 (18I3) Rabbit Monoclonal Antibody
别名
EWS; Ewsr1; RNA binding protein EWS;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q01844
免疫原
A synthetic peptide of human EWSR1
稀释度
WB: 1:1000-1:5000 IHC: 1:50-1:200 ICC/IF: 1:50-1:200
注意事项
EWSR1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
细胞定位
Nucleus. Cytoplasm. Cell membrane. Note=Relocates from cytoplasm to ribosomes upon PTK2B/FAK2 activation
功能
Might normally function as a transcriptional repressor. EWS- fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.
