RM6109

EBF1 (6I9) Rabbit Monoclonal Antibody

COE1; EBF; Ebf1; O/E 1; OE1; OLF1;

Affinity-chromatography

常规抗体

EBF1

COE1, EBF

WB

Human,Mouse

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

1879

Q9UH73

WB 1:500~1:1000

64kDa

Rabbit IgG

EBF1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.

Nucleus.

Key pioneer transcription factor of B-cell specification and commitment (PubMed:27807034). Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B- cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage. In addition to its role during lymphopoiesis, controls the thermogenic gene program in adipocytes during development and in response to environmental cold (By similarity).

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