产品名称
Hex (1A16) Rabbit Monoclonal Antibody
别名
HEX; HHEX; HMPH; PRH; PRHX;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q03014
免疫原
A synthetic peptide of human Hex
注意事项
Hex Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Liver and promyelocytic leukemia cell line HL-60.
细胞定位
Nucleus {ECO:0000250|UniProtKB:P43120}.
功能
Recognizes the DNA sequence 5'-ATTAA-3' (By similarity). Transcriptional repressor (By similarity). Activator of WNT-mediated transcription in conjunction with CTNNB1 (PubMed:
20028982). Establishes anterior identity at two levels; acts early to enhance canonical WNT- signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL (By similarity). May play a role in hematopoietic differentiation (PubMed:
8096636).
