产品名称
USP22 (13N18) Rabbit Monoclonal Antibody
别名
Ubiquitin carboxyl terminal hydrolase 22; Usp22; USP3L;
纯度
Affinity-chromatography
存储缓冲液
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% New type preservative N and 0.05% BSA.
Human Swissprot No.
Q9UPT9
免疫原
Recombinant protein of human USP22
稀释度
WB: 1:1000 ICC/IF: 1:20 IP: 1:20
注意事项
USP22 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
组织表达
Moderately expressed in various tissues including heart and skeletal muscle, and weakly expressed in lung and liver
细胞定位
Nucleus {ECO:0000250|UniProtKB:Q5DU02}.
功能
Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
